Hi buddah001 and

to TR.
I agree that bigger is easier but the all in ones are convenient. The first thing you will want to do is ditch the "built in
wet/dry filtration" (which probably means bio-balls) mentioned on every site I looked at if you want to keep anything besides fish. I have also removed the sponge that was included with my NanoCube. Besides what is in the box you will need a heater, thermometer, another small powerhead,
live rock (or live + base rock), test kits, and salt. I prefer having sand in my tanks but you can go bare bottom. You may want to purchase an
RO/DI unit although you can buy water at the
LFS or some grocery stores.
Although techniques for discus and
SW are not the same your experience with those beauties will have taught you the importance of good husbandry. This is really critical with a nano size tank because because the small volume of water doesn't leave you room for sloppy technique.