wireless/wired would be similar work, wireless would only add the complexities if you are using WEP or WPA.
my thoughts are it would be easier to run a long Ethernet cable than get a
PC close to my tank since there is a limit to the length of USB cables you can get. all my tanks are downstairs, where i have no close by computer. running a Ethernet cable would not be a big deal, but a USB cable? yeah, that would not be easy or even possible.
it would be even easier with wireless.. that said, i think the difference in wired or wireless is minor. most of the development at a high level is the same. the whole back end web delivery interface woudl be the same, only the controller hardware would need to be modified to accept the handle the wireless interface